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Nicotinic cholinergic system and COVID-19: in silico identification of interactions between 7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins

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One reason behind this interaction is ibuprofen's effect on inhibiting platelet function and impairing the blood's ability to clot (per Drugs.com), meaning that their effects might add up