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WARNING: This product contains chemicals, including nicotine, which is known to cause birth defects or other reproductive harm

Studies suggest that the nicotinic receptors involved in the cholinergic immune response play a key role in neuroinflammatory diseases such as multiple sclerosis, Alzheimers, and Parkinsons disease and nicotine has produced a variety of positive effects in a multiple sclerosis mouse model

A 5mg version was also sold in Japan, but it was soon discontinued

Vaping has been linked to severe lung injuries, such as EVALI, and conditions like popcorn lung. Smoking is a major risk factor for heart disease and stroke, and vaping also poses cardiovascular risks, including increased risk of heart disease and stroke, though the mechanisms may differ