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Description
In smokers volar forearm skin, we found increased epidermal differentiation, which may represent a compensatory mechanism induced as an adaptive response to environmental toxins such as PAHs present in cigarette smoke, or nicotine, both of which have the ability to stimulate keratinocyte differentiation
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After applying these criteria, 1366 patients from 23 districts of Rajasthan (Ajmer, Alwar, Barmer, Bharatpur, Bhilwara, Bikaner, Bundi, Churu, Dausa, Dhaulpur, Hanumangarh, Jaipur, Jalor, Jhunjhunu, Jodhpur, Karauli, Kota, Sawai Madhopur, Nagaur, Pali, Sikar, Shri Ganganagar, Tonk) were included in the final analysis

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