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Using both together significantly raises cancer risks, especially for oral and esophageal cancers

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Chemicals like pyridine and acetaldehyde are added to help increase the impact nicotine has on the nervous system they increase mood and also heighten the addictive nature of the cigarette

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These results suggest that the injury caused in the epithelium barrier can lead to the exposure of lumen antigens, which can be recognized by immune cells whose recruitment is increased, inducing the development of CD (Figure 1)