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Furthermore, studies showed nicotine interacts with brain monoamine transporter such as serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET), a major transporter system for CNS drugs (Table 1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Roche N, Marthan R, Berger P, Chambellan A, Chanez P, Aguilaniu B, Brillet PY, Burgel PR, Chaouat A, Devillier P, Escamilla R, Louis R, Mal H, Muir JF, Perez T, Similowski T, Wallaert B, Aubier M

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Paraguay and Venezuela have witnessed an increasing demand for these devices due to their convenience and the absence of persisting smoke