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Early last century Robert Baden-Powell, the founder of the boy scouts movement wrote with sexist prescience: When a lad smokes before he is fully grown up it is almost sure to make his heart feeble, and the heart is the most important organ in a lads body

However, high-level expression and uniform yields are not always easy to achieve because of position effects and gene silencing [98,99]

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In a letter to Human Rights Watch, JTI said that it does not directly contract with tobacco growers in Zimbabwe but purchased about 6 percent of its global tobacco requirements in 2017 through third-party leaf suppliers (AOI, Universal, and Premium), accounting for 5 percent of the total tobacco grown in Zimbabwe

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