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Tobacco substances undergo first-pass metabolism in the liver, exposing the organ to a complex array of over 4000 toxic chemicals, including nicotine, nitrosamines, aromatic hydrocarbons, and various carcinogens [2,3,4]

In December 2023, the Southern African Development Community announced it would deploy a regional force to do the same

The oldest evidence of betel nut chewing is found in a burial pit in the Duyong Cave site of the Philippines, an area where areca palms were native, dated to around 4,630250 BP

Oral cancers can be aggressive and difficult to treat

The stage groups are different depending on whether HPV is involved