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This powerful initial experience also primes the brains reward system, which research shows can increase vulnerability to other drug use later on

Furthermore, compared to placebo cannabis, active cannabis reduces the amount of both cannabis and tobacco rolled in a joint indicative of downward titration
A generation ago, tobacco was a small-farm crop grown by hundreds of thousands of families across the South, a few acres at a time

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Those who received methoxsalen reported far less desire to smoke
