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doi:10.1182/blood-2016-03-643544

Heated tobacco products are especially popular in Japan, where the brand Ploom is also popular

Ledgerwood claims that because the initial hit of pleasure from cigarette smoking is felt almost instantly but quickly wears off, smokers use tobacco frequently to get the same stimulant experience. According to Bernard Le Foll, Chair of Addiction Psychiatry in the Department of Psychiatry at the University of Toronto, Tobacco addiction is primarily described as a lack of control on the use of a substance and ongoing use notwithstanding the consequences. People who get addicted to a substance will go through cravings and/or withdrawal symptoms if they stop using it for a while

500g will be dispatched in the manufacturer's original, unopened packaging