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Description
A 2005 study looked at the effects of several stimulants, including coffee and nicotine, on rectal tone

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Introduction Chemical constituents present in tobacco and nicotine products and their emissions play an important role in product toxicity, carcinogenicity, and abuse liability (e.g., appeal, palatability, and addictiveness)
Similarly, no extrapolation to long-term effects on past users can be drawn from the present dataset

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