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The reason for this is due to a vasodilation (widening of the blood vessels) which allows more blood to be diverted to the brain and parts of the body that need it

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It binds to nicotinic acetylcholine receptors (nAChRs), which are integral to the nervous systems communication pathways

It obviously pays to give it some downtime rather than simply working it into the ground, but a robust unit can stand up to plenty of use

Most e-liquid flavourings are synthetic and do not contain actual nut proteins