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They should not, however, be used as a safe alternative to tobacco use

The manufacturing operations and research-and-development facility are located in Winston Salem

To clarify the effectiveness of tobacco weight reduction through decreased circumference on yields of individual sidestream smoke constituents, three 1-mg ISO tar yield ECs (K111, D111 and S111) were manufactured that differed in circumference, but maintained the same 1-mg ISO tar yield, tobacco blend and cigarette design (other than changes in filter pressure drop and paper permeability necessary to achieve the same ISO tar yield across the three cigarettes

Humidity: High coastal humidity makes the vapor feel heavier in the lungs, which some ex-smokers actually prefer, as it mimics the weight of real smoke

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