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However, this impression is largely misleading

Many ENDS devices are rechargeable and refillable, allowing users to create their own e-juice flavor and vary the nicotine levels

Its no wonder it was used as the tagline

According to the article, nicotine is mainly a potent activator of midbrain dopamine reward pathway, and its action on the locus ceruleus activates awareness, provocation, and attentiveness with anxiety activity, making nicotine users more attentive and creating dependency similar to other addictive drugs like cocaine and heroin

in 2020, which could translate into millions of pieces of plastic, aluminum, lithium ion, and packaging that ends up in landfill