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Chapter 2

Furthermore, the experimental and self-report measures used in our study focus on different aspects of norms

doi: 10.1136/tobaccocontrol-2016-053334
The chronic administration of the antidepressant and selective norepinephrine reuptake inhibitor desipramine decreases the sensitivity of presynaptic 2 -adrenoceptors in depressed patients, which lead to the 2 -adrenoceptor supersensitivity hypothesis (Charney et al., 1981

Nicotine stimulates the release of norepinephrine along with dopamine and serotonin, which is one reason why people feel more awake and focused after using nicotine