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These chemicals cause blood vessels to narrow, lessening the supply of oxygen and nutrients to the lips, which may cause them to appear dull and darker over a long period

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Nicotine acts as a gateway drug on the brain, and this effect is likely to occur whether the exposure is from smoking tobacco, passive tobacco smoke, or e-cigarettes. LEARN MORE: Why Nicotine is a Gateway Drug LEARN MORE: A Molecular Basis for Nicotine as a Gateway Drug LEARN MORE: Nicotine as a gateway drug: Biological mechanism in mice identified LEARN MORE: Why are politicians still referring to marijuana as a gateway drug

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