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1 This led eventually to a rapid increase in male lung cancer, particularly in the United Kingdom (where the disease became by the 1940s a major cause of death)
The persistence of heightened risk in former smokers has important implications for lung cancer screening given that 40.8% of the lung cancers in former smokers occurred after 15 YSQ, which is beyond the window of screening eligibility as currently defined
Some of these actions are specifically related to nicotine, while others are linked to the compounds released by smoking in general
Sullivan 2012, pp
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