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Nicotine significantly reduced IL-8, IL-6 and VEGF levels in keratinocytes and endothelial cells co-cultured with the serum of Bechet patients (Kalayciyan et al., 2007), indicating that nicotine has therapeutic potential in reducing systemic vascular inflammation

A study by UC San Diego showed that people aged 12 to 24 who used e-cigarettes were three times as likely to become daily cigarette smokers in the future There is also a growing body of evidence suggesting that e-cigarettes expose consumers to significant health harms, and that the tobacco industry is using them to capture a new generation of consumers, and create an image as an industry concerned by public health and wanting to reduce the harms created by decades of tobacco use

This trend has been consistent for four decades
