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For heavy cigarette smokers (25 or more a day at their last reply) the smoker versus non-smoker relative risk was 1.83 for the cohort born in the 19th century and 2.61 for the cohort born in the 20th century, corresponding, respectively, to 83% and 161% excess mortality among the smokers

Similar patterns of regular use, limited awareness of nicotine content, and moderate to high dependence have been observed among university students in several Middle Eastern countries, suggesting that this issue is a regional concern rather than an isolated finding ( Together, these findings indicate that e-cigarette dependence among university students is driven by a combination of behavioral habits, nicotine exposure, and positive perceptions of vaping, rather than intentional addiction

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