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The Bottom Line: Should You Smoke Pipe Tobacco Like a Cigarette

doi: 10.1016/S0140-6736(10)61388-8

The 2016 revised statement on e-cigarettes by the US Flavoring and Extract Manufacturers Association about these chemicals (which have been safety assessed for use in foods and beverages, but not for inhalation) is further cause for concern: The manufacturers and marketers of e-cigarettes and all other flavored tobacco products, and flavor manufacturers and marketers, should not represent or suggest that the flavor ingredients used in these products are safe because they have FEMA GRASTM status for use in food because such statements are false and misleading
We conducted this review to determine whether the program complied with its policies when awarding the agreements

A few long-term cohort trials have performed elevated PM 2.5 levels, indicating an improved effect of longer-period disclosure (116)