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The results suggest that people who regularly mix tobacco with cannabis are more at risk of psychological dependence than people who use cannabis and tobacco separately, without mixing them, or use cannabis alone, the researchers said

Moderate smokers (half a pack daily) do well with 1218mg freebase or 2535mg salt nic
PMID: 21464381

Besides nicotine, the aerosol produced by e-cigarettes also contains other toxic substances that are harmful to consumers health 4-8

Many modern devices have puff counters, which can be helpful