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[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Danov O., Wolff M., Bartel S., Bohlen S., Obernolte H., Wronski S., Jonigk D., Hammer B., Kovacevic D., Reuter S., et al

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Based on a power calculation using the Clincalc.com (ClinCalc LLC, Arlington Heights, IL, USA) sample size calculator with an assumed average BP of 120 mmHg, a BP variability of 5 mmHg, a clinically relevant difference of 6 mmHg, an enrollment ratio of 3, an alpha of 0.05, and a power of 80%, at least 28 participants, of which at least 7 in each of the cessation and relapse groups, were to be included

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66 Varenicline appeared to be equally as likely to promote smoking cessation as combined treatment with more than one form of NRT (OR, 1.06