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non-smokers 24 , and the striatum is widely considered to be a key set of brain structures that support addiction 25,26,27 , with interactions between nicotine and the mesolimbic dopamine system also well-established (for a review see 28 )

This declined substantially for both age groups in 2014, and declined again between 2017 and 2022/2023

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Its campaign also served as market research intelligence, with user comments from the Facebook and Instagram ads shedding light on why some smokers knowingly buy illegal cigarettes

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