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Estrogen has a profound impact on cardiovascular function, influencing both vascular tone (how blood vessels constrict and dilate) and the autonomic nervous system, which controls involuntary functions like heart rate

This is done through an emphasis on informed choice and "anti-teen-smoking" campaigns, [3] : 198201 although such ads have been criticized as counterproductive (causing more smoking) by independent groups

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Electronic cigarettes have been lauded, albeit controversially, as a healthier alternative to normal cigarettes, which could help to lessen the burden of disease caused by conventional tobacco smoke