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We may assume the possible mechanism of detrimental effect of smoking on CF may be because the alterations in microbiome due to airway surface liquid secretion, enhanced mucus expression, reduced mucociliary clearance induced by loss of CTFR functions
The importance of these factors reinforces the sociological view that the origins of drug use often lie beyond the individual and in the social environment

We now show that both smoking and drinking 15 or more units/week increased mortality from some of the above causes and also smoking-related cancer

Laan, M., Bozinovski, S

Results were pooled across the varieties PVH 2110, NC 196, GL 395, K 326, GF 318, CC 65, NC 299, NC 297, PVH 1452, and CC 35
