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The second highest prevalence of smoking was evidenced in the group with a ninth- to 11th-grade education, with men outnumbering women by 27%

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For cohort studies, we utilized the Newcastle-Ottawa Quality Assessment Scale for quantitative analysis, the Newcastle-Ottawa Scale was developed to assess the quality of nonrandomized studies with its design, content and ease of use directed to the task of incorporating the quality assessments in the interpretation of meta-analytic results (Supplementary material 1)

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Lewis (2018) discusses the possibility of genetic modification to achieve low nicotine levels in tobacco