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Bridging methodologies to deal with the existing and future diversity of cMRTPs, and assess them for their risk reduction potential in a pragmatic manner, it will be necessary to develop bridging methodologies that enable a scientifically sound comparison of any cMRTP with a reference MRTP

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Today, the Royal College of Physicians in the UK actually recommends that doctors encourage their smoking patients to switch to e cigs as a harm reduction strategy

doi: 10.1542/peds.2016-0379 Summary Keywords nicotine pouches, cardiovascular risk, adolescents, young adults, nicotine addiction, tobacco harm reduction Citation Abid S, Aggarwal A, Duarte F, Sethi S, Iyengar S and Zarich S (2025) Nicotine pouches and youth: emerging patterns and potential cardiovascular risks