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Medtronic, Inc., assignee

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After fully adjusting the model and controlling for associated confounders, we observed a significant negative correlation between the eGFR and cotinine [0.0083 (0.0118, 0.0047)0.000005] (Table 1 and Figure 2) and reached the same conclusion after the smooth curve fitting (Figure 1)

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Similarly, ELISA analysis showed that, compared with the CSE treatment group, transfection of MLE-12 cells with the miR-125a-5p inhibitor blocked the secretion of IL-6, IL-8, and CCL2 (Fig