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These days, the dangers that cigarettes pose to health are well-documented

Although high variation can be seen when comparing individual countries, the median maximal market share was found to have marginally decreased between 2011 and 2020

McGehee, the lead researcher testing nicotine effects on rat brains, comes to this conclusion: This suggests that in humans a relatively short nicotine exposure, even for someone who has never smoked before, can cause long-lasting changes in excitatory neurotransmission

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