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low certainty).40 Pharmacotherapy and combined behavioural and pharmacotherapy interventions Our review showed that bupropion may result in little to no harm, although data were of very low certainty or could not be evaluated for certainty because not enough data were provided.22 An updated Cochrane review on bupropion41 suggested there may be a small increase in adverse events, which could constitute a small harm (Appendix 1 and Appendix 2)

1885 King Kelly (Goodwin & Company Cigarettes 1888) Maurice Daly, US billiards champion, 1888 Chief Gall (Allen & Ginter, 1888) Amy Coleridge, before 1900 Actress, Blanche Bates, 1901 Former Australian cricket captain, Joe Darling, early 1900s Ambrose McConnell (American Tobacco, 1911) Reformer A.C

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[1] [2] In France [edit] Since March 2010, flavoured cigarettes are no longer sold in France in a bid by the French government to combat youth smoking