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Smoking-related Illnesses Smokeless Tobacco Smokeless tobacco use results in many harmful effects on health

Nicotines effects on the brain are particularly poignant in adolescent years when the brain is developing

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Behaviors that have no direct pharmacological effects produce symptoms of addiction (e.g., gambling) and may be associated with dysregulation in brain reward circuits (Quester and Romanczuk-Seiferth, 2015)

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