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The infertility rate among women who smoke more than 10 cigarettes a day is 10.7%, compared to only 5.4% for non-smoking women
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Given that IL-1RA competes with IL-1 for binding to the IL-1 receptor and prevents IL-1-induced pro-inflammatory signalling we wondered if the increased production of IL-1RA in smokers was associated with high IL-1 levels
