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[4] Due to pain during eating, weight loss may develop as a result of not eating in severe cases of aphthous stomatitis

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Alcohol, on the other hand, is a depressant, so it slows the central nervous system

UPDATE: While that's not yet clear, Episode 4 shows us that Sinatra certainly has a killer instinct: She not only tasked Billy with offing the members of the scientific mission (in order to stop them from letting Paradise know that the air topside was breathable), she had Billy himself killed when he warned her to stay away from Xavier and his family