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Furthermore, endogenous antioxidants such as superoxide dismutase and catalase were also lower in smokers.56,100 Seminal plasma Zn also plays an important role as antioxidant and antibacterial agent that protect the semen from heavy metals accumulation.21 Compared with fertile nonsmokers, fertile smokers were significantly associated with lower seminal Zn levels.56 Kiziler et al .94 utilized statistical methods to verify the correlation between semen oxidative stress and Cd/Pb exposure