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Furthermore, some early studies have demonstrated that nicotine may also directly inhibit the formation of amyloid plaques in Alzheimers

There is clearly a need for increased forms of nicotine delivery, possibly including those that more closely mimic the pharmacokinetics of cigarettes

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Dendritic cells are well-known as the most professional APCs with high expression of major histocompatibility complex (MHC) class II molecules (MHC-II), and they can uptake, process, and present antigens to nave T cells and promote their polarization into different T cell subsets [115]
