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Poly(dimethylsiloxane) (PDMS), a standard polymeric material used for the fabrication of microfluidic devices by master-replication techniques, was already shown to allow a site-specific bottom-up integration of TMV carrier sticks [60]

31 Rodriguez, D, et al., Predictors of tobacco outlet density nationwide: a geographic analysis, Tobacco Control,published online first on April 4, 2012.See also Lee, JGL, et al., Inequalities in tobacco outlet density by race, ethnicity and socioeconomic status, 2012, USA: results from the ASPIRE Study, Journal of Epidemiology and Community Health, published online March 1, 2017 32 US Department of Health and Human Services

As it interacts with the brains reward centers, nicotine can lead to a cycle of withdrawal and reduced sensation when smoking

Directed evolution of the luciferase from the deep-sea shrimp Oplophorus gracilirostris led the creation of NanoLuc luciferase in 2012, which has since been used for a variety of research, ranging from clinical drug development to studies of neurodegenerative diseases

Genome sequencing and highthroughput genotyping enriched the toolkit of quantitative genetics, enabling deeper analysis of genetic variation in natural populations and precise selection based on genomic breeding values