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Men and women ages 40-59 who smoked had about a 10% higher risk of developing some type of cardiovascular disease than those who didn't smoke

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Two main polarisations of TAMs include M1-like macrophages, which exhibit anti-tumour activities by stimulating the adaptive immune response and inflammation and, conversely, M2-like macrophages, which exhibit tumour promoting activities by suppressing the immune response in the TME [183]