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Description
In silico analyses confirmed the antiglycation properties of propranolol during its interaction with glycosidases (e.g., -amylase, -glucosidase and sucrase-isomaltase) and proteins of the AGE/RAGE pathway, including RAGE, NF-kB, PI3-K and mTOR

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According to Steenburgen, she, Caan and even Ferrell would sometimes "ruin a take a little bit from laughing," because "the visual" of Ferrell in costume as Buddy "was constantly funny." "You didn't really get used to it," she told PEOPLE