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In 12 states a region we call Tobacco Nation that spans Alabama, Arkansas, Indiana, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Ohio, Oklahoma, Tennessee, and West Virginia both adults and young adults have 50% higher smoking prevalence and smoke many more cigarettes per capita annually than people living in other states

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NBC News' Kasie Hunt contributed to this report

Some experts believe that any drug could be a gateway drug if it is used early in life

In smoking, on the contrary, oxygen breaks down the organic matter in the tobacco, releasing heat and combustion gases, water, and carbon dioxide