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PMID 28292008

Selling Smoke: Tobacco Advertising and Anti-Smoking Campaigns Item Longhorns Title Longhorns Description A pack of Marlboro 100s, featuring small photos of a cowboy and a longhorn steer Creator Marlboro Publisher Philip Morris Date 1967 Source Image from the William Van Duyn Tobacco Advertisement Collection (Ms Coll 20), Medical Historical Library, Harvey Cushing/John Hay Whitney Medical Library, Yale University

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Given that electronic cigarette use has been associated with cognitive effects, such as depression ( Alterations to CYP450 enzyme function and drug interactions Cytochrome P450 (CYP450) enzymes play a critical role in drug metabolism, especially for therapeutic compounds used to treat symptoms associated with depression and other psychiatric disorders