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The Charlson Comorbidity Index (CCI) was used to quantify the burden of 17 comorbidities (acute myocardial infarction, congestive heart failure, peripheral vascular disease, cerebral vascular accident, dementia, pulmonary disease, connective tissue disorder, peptic ulcer, liver disease, diabetes, diabetes complications, paraplegia, renal disease, cancer, metastatic cancer, severe liver disease, and HIV) ( Statistical analyses Categorical data are expressed as percentages, and continuous data were summarized as means and standard deviations

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