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PMC 1603361
While you can make one by hand, the results are never that good so we would always recommend using a filling machine
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Bennett, When Tobacco Was King: Families, Farm Labor, and Federal Policy in the Piedmont (Gainesville, FL: University Press of Florida, 2014), 8-9, 28-32
According to Liu, their study is the largest genetic study on smoking and drinking behaviors to date, and is the most ancestrally diverse
