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Within the heated tobacco cartridge, these materials function as carriers for nicotine, smoking agents, essence and flavor, and tobacco concentrate

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The FDAs advance notice of proposed rulemaking on a tobacco product standard for nicotine level of combusted cigarettes sought comments on nicotine levels in the range of 0.30.5 milligrams of nicotine per gram of tobacco filler (83 FR 11818, 2018)