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Additional covariates for exacerbations included FEV 1 % predicted, SGRQ, and gastroesophageal reflux disease (GERD).18 , 19 Exacerbations in the year prior to enrollment (retrospective) and during longitudinal follow-up (prospective) were modeled using negative binomial regression with an offset for exposure time and zero-inflated negative binomial (ZINB) regression to account for the excess number of subjects who reported no acute episodes of respiratory disease (see18 for a description of modeling exacerbations)

Across the devices we tested, the standout disposable vape flavors are icy fruit blends (the Geek Bar Pulse X does these best), balanced fruit-and-cooling mixes on the Raz LTX 25K, and sweet candy or dessert profiles on the Beri Crush

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We also dont yet have decades-long data on the long-term health effects of chronic vaping, which is reason enough to be cautious, especially for young people and non-smokers

If they won't turn smoothly, there's debris or damage that needs addressing