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Also, unless urgent action is taken, the annual death toll for tobacco-attributable causes could rise from 60 lakh to more than 80 lakh by 2030

A valid-PRS established based on such a process thus fulfils the definition of an instrumental variable mentioned above if it remains associated with the designated phenotype of interest

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Breathing even a little tobacco smoke can be harmful.[11] Of the more than 7,000 chemicals in tobacco smoke, at least 250 are known to be harmful, including hydrogen cyanide, carbon monoxide, and ammonia