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Second, response rates might have affected estimates
Limebeer CL

1980s: Tobacco companies deny secondhand smoke is dangerous

This means that over time, the same amount of nicotine produces a weaker effect, prompting users to consume more to achieve the initial pleasurable sensations

In a study published in the open access journal BMC Public Health , researchers from the University of North Carolina at Chapel Hill suggest that the Food and Drug Administration (FDA) expand its messaging activities so that information about these constituents reaches all segments of the US population, especially those most vulnerable to tobacco product use and its associated health risks
