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In many experimental systems, cancer induction increases in tandem with increases in specific promutagenic DNA adducts and decreases when adduct formation is blocked

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We did notice differences in cigarette consumption among regions, as you can see in the chart below (which includes both the November 2015 and February 2016 periods of the survey)

Indeed, some studies have found associations between smoking status and estrogen and progesterone [65, 68], while others showed that endogenous estrogen levels do not vary between nonsmokers and smokers [67, 69, 70]

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