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A breastfed baby receives the effects of tobacco through breast milk and smoke
Besides the induction of inflammatory macrophages, nicotine treatments promote the M2 polarization, reduces the secretion of several proinflammatory cytokines in macrophages, and suppresses the alveolar macrophages to present the inhaled antigen to lymphocytes [130, 131]

This can be a result of protein allergens of the flower, fungal sensitization [74], or other components such as mold and pesticides [75]

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These biases arise from the assignment of greater influence to closer points when spatial clustering occurs or when a data point is overly isolated [47, 48]
