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WARHOL: I dont know

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"Evidence suggests that they help people stop smoking tobacco and they are less harmful than normal cigarettes so we want to regulate them like other medicines," a spokesman for the Medicines and Healthcare Products Regulatory Agency told me

Dividing this by the average nicotine content of a cigarette (1mg) gives an equivalence of 500 cigarettes for the entire bottle, though actual usage varies
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Cleaning frequency can vary
