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Such distinctive data are also hard to obtain due to the frequent co-existence of combined risk factors

643828 Prokhorov AV, Hudmon KS, Stancic N (2003) Paediatr Drugs 5:110 Pryor WA, Stone K, Zang LY et al (1998) Chem Res Toxicol 11:441448 Richter E, Engl J, Friesenegger S et al (2009) Chem Res Toxicol 22:10081017 Rodgman A, Perfetti T (2009) The Chemical Components of Tobacco and Tobacco Smoke

Dependence can be divided into two types: psychological dependence, by which a user experiences negative psychological or emotional withdrawal symptoms (e.g., depression) and physical dependence, by which a user must use a drug to avoid physically uncomfortable or even medically harmful physical withdrawal symptoms

Rubinstein et al., 2018

Betelnut, Catechu, Lime, Cardamom Seeds and Saffron,Natural Flavours and Natural Flavouring Substances
