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The link between nicotine addiction and other substance use disorders is that nicotine addiction serves as a gateway to other substance use disorders, as individuals who are addicted to nicotine incur a higher susceptibility to alcohol and drug use

While all tobacco and nicotine products fall under the Food and Drug Administration (FDA)s regulatory authority, not all are regulated the same

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This narrative review summarizes evidence published up to May 2025 on the epidemiology, health effects, and prevention of e-cigarette use in children and adolescents